Possible Side Effects of Testosterone Injections

Testosterone is a sex hormone which is most commonly produced by males from the testicles. However, small amounts of testosterone are also produced in women. In women it is produced by the ovaries and the adrenal system. The deficiency of this hormone may call for the need to use testosterone injection.

Testosterone is produced by the body and contributes to the growth, development, and functioning of the male sexual organs and typical male characteristics.

Possible side effects of steroid injections

Possible side effects of steroid injections

What is testosterone injection?

What is testosterone injection? Testosterone injection is used in males for the treatment of various conditions caused by testosterone deficiency. Some of the conditions may include, delayed puberty, impotence, or other hormonal imbalances. The injection is also used in women to treat breast cancer that has spread to other parts of the body.

How testosterone injections work

How does this injection work? Testosterone injection works by supplying synthetic testosterone to replace the testosterone that is normally produced naturally in the body. When this hormone is used to treat breast cancer, testosterone works by stopping the release of estrogen.

Testosterone injections deliver testosterone into the muscle. The testosterone is then absorbed directly into the blood stream over time. The absorption period depends on the type of testosterone injected. Injections usually take place in the thighs, glutes or deltoid muscles.

Most common side effects of testosterone injections

The use of testosterone injections helps so much in the treatment of various conditions caused by testosterone deficiency. However, prolonged use of these injections may be accompanied by undesirable side effects some of which may be very serious. Therefore, the users of these injections ought to be very careful. Below are some the side effects of using testosterone injections;

Increase in the number of red blood cells

Testosterone injections activate spleen cells causing them to produce more red blood cells than the normal level in the body. The high concentration of red blood cells in the body makes the blood to be thick thereby making it hard to circulate around the body. This extra red blood cells also means that the supply of oxygen to the blood from the air sacs of the lungs should be more than the normal rate. This condition can lead to stroke or heart attack.

Sleep disorder

Sleep disorder is caused by hormonal imbalance in the body. The use of testosterone hormones greatly the increase the level of this hormone in the blood. This may cause one to sleep like a baby. People with more of this hormone usually experience tend to sleep more. However, sleep disturbance is as a result of testosterone deficiency.


This is a deep emotional feeling of sadness. When testosterone injections are administered in high dosage, it disrupts the hormone balance in the body making the body to respond negatively to situations. This makes an individual to lose interest in the activities enjoyed earlier on. Other symptoms of depression include, loss of appetite, weight fluctuation, and oversleeping.

Lower sperm count

Sperms are normally synthesized in the testes. The use of testosterone injections raises the level of testosterone hormone in the body. The high amounts testosterone hormone in the body results into lower sperm count.

The high levels of this hormone overwhelms the male reproductive system thus causing reproductive problems. This condition may persist until the level of testosterone is reduced.

Causes prostate changes

Prostate is a small but important gland in the male reproductive system. The main role of the prostate is to make fluid that protects and feeds sperm. The prostate makes about one third of the fluid that is released from the penis at orgasm.

The male sex hormone testosterone makes the prostate grow in size. The use of testosterone injections makes the prostate grow larger. This is due the increased levels of testosterone levels in the body that and the prostate grows more times than the normal size.

Causes anger

High levels of testosterone hormone in the body causes uncontrollable anger. When hormones are unbalanced in the body, it very hard for men to control their emotions. This may lead to physical fights, destructions and damage of property.

Enlargement of breasts

Enlargement of the male breast, comes about when there’s an imbalance between male hormone and female hormone. In aged men, the low level in the production of testosterone allows their natural estrogen to increase breast growth.

Men who normally take testosterone supplements, like AndroGel, often experience breast enlargement. The reason behind this is that, some of the male hormone is transformed into female hormone, and that female hormone present in the body naturally stimulates the enlargement of breasts.

Testicular changes

The use of excess testosterone hormone injection causes the shrinking of testicles. The reason behind this is that, testosterone hormone is normally produced in the testis. When the levels of testosterone hormone in the body becomes too high, the function of the testicles ceases.

It is therefore obvious that the testicles become dormant due to the presence of high levels of testosterone in the blood. This completely brings down all the activities in the testes making them to shrink. To avoid this problem, one should ensure that the right dosage is used and frequent use of these injections should be avoided.

Increased or decrease interest in sex

Testosterone hormone is responsible for controlling sex drive in men. The decline in this hormone cause decrease in sex drive. However, the use of testosterone injection in men increase the levels of this hormone in the body. This causes men to experience increase in their interest to have sex.

Other side effects of testosterone injections

Testosterone injection has many other side effects some of which may not be that serious and do not necessary need medical attention. Some which is, acne,  pain, hoarseness, deepening of voice, pain or redness at injection site, tiredness, lack of appetite, mood swings, irritability, itching skin, indigestion, gum pain or blisters, euphoria, noisy breathing, paranoia, slow or fast heart beat and many more.

Regardless, testosterone injections given in specialist hormone therapy clinics such as TRT Medical Center have been proven to help in treating its deficiency. Testosterone deficiency in men comes with symptoms such as decreased hair on the body, weak bones, drops in muscle mass, mild anemia etc.

Sources and references

  1. com: Testosterone injection
  2. WebMD: Is Testosterone Replacement Therapy Right For You?
  3. COM: High Testosterone Symptoms in Men

MedlinePlus: Testosterone injection